منابع مشابه
Anchorage-dependent Cell Cycle Progression
T he concept of anchorage-dependent growth and the close relationship between anchorage independence and tumorigenicity were first appreciated more than a quarter century ago (9, 16, 23, 24). Penman and his coworkers then showed that incubation of cells in the absence of substratum (e.g., tissue culture plastic or purified extracellular matrix protein [ECM]) resulted in an inhibition of mRNA pr...
متن کاملEffects of Over-Expression of LOC92912 Gene on Cell Cycle Progression
Background: We had previously identified the genes involved in squamous cell carcinoma of the head and neck using differential display and DNA microarray techniques. We also reported the first analytical study on a novel human gene called LOC92912, which was identified by differential display as a gene up-regulated in such carcinomas. LOC92912, which is a putative member of the E2 ubiquitin con...
متن کاملAnti-proliferative Effects of Prunus Armeniaca Semen on Acute Leukemia by Regulate of Cell Cycle Progression
Introduction: Prunus armeniaca is one member of the Rosaceae family. Antitumor activity of this family on the colon, prostate, bladder, cervix, lung and breast cancers has been proven in previous research, which is attributed to a natural compound called amygdalin. Therefore, in this study, we investigated the effect of apricot kernel extract on acute leukemia that has not been studied before. ...
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Objective(s): T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematologic malignant tumor. Administration of chemical compounds influencing apoptosis and T cell development has been discussed as promising novel therapeutic strategies. Valproic acid (VPA) as a recently emerged anti-neoplastic histone deacetylase (HDAC) inhibitor and pioglitazone (PGZ) as a high-affinity peroxisome p...
متن کاملCell cycle progression towards Alzheimer's disease.
A l z h e i m e r’s disease (AD) is an incurable degenerative dementia, which affects several million patients worldwide (1). A small percentage of cases are familial, in that they have been traced to autosomal dominant inheritance of mutations in three genes: the β-amyloid precursor protein (APP) (2), and the presenilins (PS1 and PS2) (3). All these defined causes of AD lead to an increased pr...
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ژورنال
عنوان ژورنال: Circulation
سال: 1998
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.98.1.82